@article{ganusov_mathematical_2013,
 abstract = {Human immunodeficiency virus (HIV-1 or simply HIV) induces a persistent infection, which in the absence of treatment leads to AIDS and death in almost all infected individuals. HIV infection elicits a vigorous immune response starting about 2-3 weeks post infection that can lower the amount of virus in the body, but which cannot eradicate the virus. How HIV establishes a chronic infection in the face of a strong immune response remains poorly understood. It has been shown that HIV is able to rapidly change its proteins via mutation to evade recognition by virus-specific cytotoxic T lymphocytes (CTLs). Typically, an},
 area = {hiv_evolution},
 author = {Ganusov, Vitaly V. and Neher, Richard A. and Perelson, Alan S.},
 date = {2013-01-16},
 doi = {10.1088/1742-5468/2013/01/P01010},
 issn = {1742-5468},
 journal = {Journal of statistical mechanics (Online)},
 keywords = {acute HIV infection, cost of escape, CTL response, escape mutations, mathematical model},
 language = {eng},
 month = {January},
 pages = {P01010},
 pdf = {ganusov_mathematical_2013.pdf},
 pmcid = {PMC3961578},
 pmid = {24660019},
 title = {Mathematical modeling of escape of {HIV} from cytotoxic {T} lymphocyte responses.},
 volume = {2013},
 year = {2013}
}