neherlab@biozentrum
  • Home
  • Outreach
  • Publications
  • Software
  • Talks
  • Teaching
  • Team

Intermediate phase in DNA melting.

Richard A. Neher and Ulrich Gerland

Physical review. E, Statistical, nonlinear, and soft matter physics, vol. 73, 030902, 2006
10.1103/PhysRevE.73.030902

Abstract

We predict a temperature-driven phase transition of DNA below the melting transition. The additional, intermediate phase exists for repetitive sequences, when the two strands have different lengths. In this phase, the excess bases of the longer strand are completely absorbed as bulge loops inside the helical region. When the temperature is lowered, the excess bases desorb into overhanging ends, resulting in a contour length change. This continuous transition is in many aspects analogous to Bose-Einstein condensation. When the sequence is weakly disordered, the contour length changes discontinuously with temperature.


Publication date

Jan 25, 2006
10.1103/PhysRevE.73.030902
Jan 25, 2006

bibtex

  • Imprint
  • Powered by Pelican. Theme based on: Elegant by Talha Mansoor